Activation of Silent X Chromosome Might Improve Cognition
Using a mouse model, researchers from UCSF have found that the genes that become activated on the silent X chromosome might explain some sex-dependent differences in cognitive abilities during aging [1]. XX and XY It is widely known that women live longer than men [2]. Women also show differences in cognitive aging [3]. “In typical aging, women […]
Scientists Create Cytoskeleton-Like Structures From RNA
In a new study, researchers report producing self-assembling nanotubes and rings made from RNA molecules inside artificial cell-like lipid vesicles. In the future, this technology could facilitate the creation of synthetic cells for various research, diagnostic, and therapeutic applications [1]. Paperless origami DNA and RNA molecules are central to life, carrying essential genetic information for protein production. […]
Urolithin A: The Promise and Reality of a Gut Metabolite
Urolithin A is a natural metabolite produced by gut bacteria that break down polyphenols in food. While there has been a significant amount of interest and hype around urolithin A supplements, we take a look at the reality to see if it measures up. Life, longevity, and a bit of fruit juice In the days […]
Need for Cholesterol May Explain Alzheimer’s Brain Patterns
Why do some parts of the brain succumb earlier? Despite decades of research and vast amounts of funding, scientists still have limited understanding of how Alzheimer’s disease develops and progresses. The field urgently needs new approaches, and a recent study from the University of California, San Francisco, published in Alzheimer’s and Dementia, is an example of […]
Changes in Aging Adrenal Glands Disturb Hormonal Balance
Small but vital This paper begins with an in-depth description of the anatomy of the adrenal glands, which sit atop the kidneys, and the various hormones that each of their four zones produces; only the inner portion of these glands is responsible for adrenaline itself. The levels of these hormones vary with aging; some are […]
Heat May Speed Up Epigenetic Aging in Older Adults
A recent study reported significant associations between increased heat days and accelerated epigenetic aging [1]. Heat alters DNA While warm summer days on the beach are pleasant, extreme heat is not as enjoyable, especially in daily life. It is also not healthy, since extreme heat has been linked to cardiovascular diseases and death [2, 3]. DNA methylation […]
